Munchner corona anti-body study: infection mortality rate “many about the for seasonal flu infections”

Munchner Corona anti-body study: Infection mortality rate'vielfaches uber der fur saisonale grippeinfektionen'

SARS-CoV-2. Image: NIAID / CC BY-2.0

In the first wave, the number of infected four times was high than that of the positive tested. In the gangelt study, she was five times high, but the infection mortality at 0.37 percent, in Munchchen at 0.76 percent

In the spring year, after a study, the number of Covid-19 was four times high than the positive tested. This is the result of the roughly applied anti-body study (KOCO19) under the direction of the tropical institute of the LMU. She was designed to collapse the dark figure of infection from a representative and randomized part of the population of Munchens. 5313 Munschern Over 13 years, blood samples were taken several times over the period from the beginning of April to the beginning of June and examined with three different tests on Corona anti-body.

In time, 6584 was officially infected in Munchen, 0.4 percent of the population. "Taking into account the selection procedure and the differences between the study population and the Munchner population" the scientists came to the treasure that until the beginning of June, 1.8 percent of Munchner population anti-body have trained the treasure that. Overall, the 25 were allowed to.000 Munchner have been infected. The IgG anti-corporary were still detectable after months.

A similar study was under the direction of prof. Dr. Hendrik Streeck has been carried out by the University of Bonn in Gangelt six weeks after a mass outbreak due to a carnival session. Here were 919 participants from 405 randomly selected households, 15 percent of the inhabitants, from the end of Marz until the beginning of April, blood samples for an anti-body test was taken. In tangled, the number of infected ones was even fifeless as high as the officially recorded. In contrast to Munchchen, a hotspot had been a hotspot. 22 percent were asymptomatic.

"Low dark figure of Covid-19 associated death traps"

The study in Munchen took it very well with the random and representative selection of the participants. First, 100 Munchner voice districts were selected representative: "On a predetermined route, the student teams excluded from the geographic center of each of the 100 voice districts about 30 households." In multi-family homes a flat has been selected per floor. The households were then written and asked for participation. Of 5320 invited households participated in the study with 5313 residents at the study. That’s the scientist "Good with Munchner overall coverage over 13 years comparable".

But not quite representative, since 82 percent of the participants were born in Germany, but in the total taxation, this is only 69%. And since under-13-year-olds from ethical reasons did not participate in the study, this could also dismiss the estimation. Anyway, it was found that there are no risk groups for an infection with the participants. There was a light, but statistically non-significant hanging in households. And the scientists, they could largely notice a cross-reactivity with harmless sniff coronaviruses because they were very small.

Of course, that of the infection mortality rate (IFR) results from the treasured dark figure of infected. Due to the anti-corporate findings and the officially reported COVID-19 death, the scientists calculated an IFR of 0.76, whereby it can be less or more (95% confidence interval 0.59% -1.08%). The goods significantly higher than normal flu waves that have an IFR of 0.1 percent or lower (as danger is COVID-19 compared to seasonal flu?To).

The LMU scientists have also analyzed the surprises of Marz to June. At the beginning of April there was a significant overlimity, but quickly dropped back until early May. The officially reported SARS COV-2 death trap shot into the high in mid-April to bring back to a normal death rate by June. For the surprises, the scientists clearly make COVID-19 responsible. But they come to the end that "The comparison of overlimity and the registered number of COVID-19 associated death traps to a low dark figure of Covid-19-associated death traps" point.

And what has the gangelt study resulted in? Here, the scientists came to a significant lower IFR of 0.37 percent. The Munchner scientists say: "The mortality at Covid-19 infections lies according to our data with just under 1% of the people with anti-corporation by a multiple about the for seasonal flu infections." From this one can only conclude that further studies are necessary.

And of course, now, where much more is tested, do not just say that four times as many people are still infected as officially tested positive. The dark figure was allowed to be lower.

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